ABSTRACT
Multisystem Inflammatory Syndrome associated with COVID-19 infection in children (MIS-C) is a severe, life-threatening, rapidly evolving condition that occurs 3 to 4 weeks after infection with the SARS-CoV-2 virus. It results in persistent fever for more than 4 days and severe inflammation of many organs - heart, lungs, eyes, skin, kidneys, brain, blood vessels, gastrointestinal tract, etc. mainly in older children and adolescents without previous underlying chronic diseases. This syndrome requires rapid and accurate diagnostics in order to initiate treatment with properly selected immunomodulatory, anticoagulant, antiplatelet, infusion, antibiotic and cardiotonic therapy. The proper assessment of the clinical and laboratory values together with adequate treatment leads to complete recovery without complications. The aim of this study is to share our experience in diagnosis, treatment and follow up of the first four children with MIS-C, who were treated at the Paediatric clinics of the Department of Paediatrics at the University Hospital “Sveta Marina”, Varna. Detailed knowledge of this novel disease is responsibility of every Paediatric clinic in the current Corona virus pandemic situation. © 2021 Academy of Medicine. All rights reserved.
ABSTRACT
Multisystem Inflammatory Syndrome in children related to COVID-19 (MIS-C) is a new condition the aftermath of which is yet to be studied both in Bulgaria and globally. We present a 15 years old patient with MIS-C, diagnosed with acute abdomen, operated and consequently treated for septic shock syndrome, with late diagnosis and favorable outcome with standard treatment at a Pediatric Intensive Care unit. Early detection and timely diagnosis by testing for early inflammatory markers such as procalcitonin, serological testing of IgM and IgG antibodies for SARS-CoV-2 and multidisciplinary collaboration can significantly alter the complications of this serious condition. Clinical experience and standard therapeutic strategies will decrease the mortality, the need of intensive care as well as prevent the long-term consequences in the affected patients. © 2021 Academy of Medicine. All rights reserved.